850
ELEMENTS OF MATERIA MEDICA.
Brandes’s Analysis.
Fatty oil . 24 2
Waxy fat . . . 1-4
Resin insoluble in ether . 3-0
Malate of hyoscyamia with ma-lates of lime and magnesia,and a salt of potash and am-monia . . . 6-3
Uncrystallizable sugar .a trace
Gum l - 2, Bassorin 2'4, andStarch T5 . . 5-1
Albumen . . . 4\5
Vcgeto-animal matter . 3 4
Malate, phosphate, sulphate,andmuriate of potash . . 0-4
Malates of lime and magnesia . 0-6
Phosphates of lime and magnesia 2 - 4
Woody fibre . . . 26-0
Water . . . 24T
Lindbergson’s Analysis-
Narcotic extractive soluble in "and alcohol.
Bitter extractive.
Gummy extractive. an J
Malates, phosphates, sulphates,muriates of potash and magn®*^_
Extract of the herb.
aiM 1
The ashes contained carbonate, phos-phate, sulphate, and muriate of potash,carbonate and much phosphate of lime,much silica, manganese, iron, and mi-nute traces of copper.
1. Hyoscyamia or Hyoscyamina. —This term has been applied to a vegetable \ ra l-procured from the seeds and herb of Hyoscyamus niger by Brandes ( Pharm■ j jj t . s se»Blatt fur 1832, S. 479), whose statements have been confirmed by Geiger an lJ. j# 30 ias well as by Mein (Journ. de Pharm. t. xx. p. 87, and Pharm. Centr.-Blatt J u v>; i.S. 83). However, Chevallier, as well as Brault and Poggiale (Journ. de Pharm '.
p. 134) have failed to procure it. The properties assigned to it are almost* jt iswith those of Atropina , from which it differs in being more soluble in wa ^ T \ s ing efcrystallizable, has an acrid taste, and, when volatilized, yields ammonia. . g { tb' 9(Arch. Gin. de Mid. t. xviii. p. 301) says, that a drop of a solution of onegr ain . e r jsesubstance in ten grains of water causes dilatation of the pupil, but does not gto irritation of the eye. A solution of double this strength acted as an irritant. pr-
2. Empyreumatic Oil of Henbane (Pyro-Hyoscyaminaf). —This was obtaine. j 0 n 0 'Morries (Ed. Med. Surg. Journ. vol. xxxix. p. 379) by the destructive ^ ,- c oilhenbane. Its chemical properties are identical with those of the empyreumatifoxglove. It proved a powerful narcotic poison.
« • -
Physiological Effects, (a.) On vegetables. —Water holding
ous to Hyoscyamus niger (A*- a
Gi'fits
tion extract of henbane proved poisonous to Hyoscyamus nigerquoted by Decandolle, Phys. Veg. p. 1354).
(b.) On animals. —Its effects on herbivorous animals are slight- „to horses, in large quantities, it causes merely dilatation of the!) bspasmodic movements of the lips, and frequency of pulse «•
Pharm. Vet. p. 349: see also Viborg, in Wibmer’s Wirk. d. A?"yjGift. Bd. iii. S. 156). On dogs its effects appear to be analogn. 0ll ,those on man (Orfila, Tow. Gen.) It does not cause any local oS te'Its constitutional effects are, dilatation of pupil, weakness of the Yrior extremities, staggering, and insensibility. . , e a nd
(c.) On man.—In small and repeated doses henbane has a sedati^.^tranquillizing effect. This is especially observed in persons sU ^ ^with great nervous irritability, and with a too active condition tel) -sensorial functions. In such it frequently causes calmness, with -^i-dency to sleep. It frequently allays irritation and preternatural ® geC re'lity existing in any organ. It does not quicken the pulse, chec