ELEMENTS OF MATERIA MEDICA.

1012 C'n'

5. Extractum Cinchona, E.— (Take any of the varieties of .chona, but especially the Yellow or Red Cinchona, in fine P?'' cli'stdProof Spirit, fjxxiv. Percolate the cinchona with the spirit} aU 0 peRthe greater part of the spirit; and evaporate what remains Wvessel over the vapour-bath to a due consistence). , p,.j. >

Extractum Cinchonas, D.— (Pale Bark, coarsely povvdereWater, Ovj. Boil for a quarter of an hour, in a vessel almost C boil thethen having filtered the liquor while yet hot, and laid it aside,> saJO ebark again in an equal quantity of water, and filter again W 1 th®manner ; proceed in the same way a third time, and then mixingliquors, reduce them by evaporation to a proper consistence)- lC ]ioH a »Extractum Cinchonas cordifolia, L. — (Heart-leaved Ct “ofbruised, gxv.; Distilled Water , Cong. iv. Boil down m a gad llia nn erwater to six pints, and strain the liquor while hot. In the same^boil down the bark in an equal measure of water four times, an .Lastly, all the liquors being mixed, evaporate to a proper consis jjjjg,Extractum Cinchona lancifolim, L.—(Prepared as the p reusing Lance-leaved Cinchona ). ,, g prc

Extractum Cinchona orlongifolia, L.—(Prepared asceding, using Oblong-leaved Cinchona ). ontai nS

The watery extract of cinchona (extractum cinchona, L. DO c , ^ Je-the same constituents already mentioned (p. 1010) as being f° u _\ ea \e&coction of bark. Mr. Brande (Diet, of Pharm. 170) says, l al ' c ® e pjjir[i. e. pale] bark yields 30 per cent, of watery extract. The ac i' rpjjeciples of this preparation are the kinates of the cinchona alkaloi • rspirituous extract ( extractum cinchona, E.) is a more efficacious p ^ pietion, as it contains, besides the alkaline kinates, the c°mp oU1 \^ reC ti'red cinclionic with the cinchona alkaloids. When prepared

fie. P ale ^

fied spirit, 24 per cent, of extract is obtained from lance-leaved L • 0 o ye0,bark. But as the Edinburgh College direct proof spirit to be e or a'tlie produce is larger.—Well prepared ( i. e. not decomposed by ea rlVtion) extract is a very useful preparation, which, however, has be ^ in

It is given in the form 0 ^ s0 iyedgr. xx. Ur the watery extract may i"

superseded by sulphate of quinia. it is givendoses of from gr. v. to gr. xx. Or the watery extract mayin water, or in infusion of roses, or, for administration tosyrup of mulberries or of orange-peel.

6. Quina Disulphas, L. E .—Sulphate of Quinine , offic-tions of the London College lor the preparation of thisfollows:—

The

are as

salt

Take of Heart-leaved Cinchona , bruised, lb. vij.: Sulphuric Acid , 3! pistilAnimal Charcoal, jij.; Hydrated Oxide of Lead; Solution of Ammonia^, ^ 0 f tnWater, each as much as may be sufficient. Mix four ounces and two dra ^ ^ tb elI j

an 1

il

Sulphuric Acid with six gallons of distilled Water, and add the Cincbou^,, ^ c j(J ^boil for an hour, and strain. In the same manner again boil what remains^.^uy,Water, mixed in the same proportions, for an hour, and again strain- \Va-

the Cinchona in eight gallons of distilled water for three hours, and s r 0* 1 ^what remains frequently with boiling distilled water. To the mixed liq u0 a „J W aS aof Lead, while moist, nearly to saturation. Pour off the supernatant h<l u ’ te r °. *what is thrown down with distilled water. Boil down the liquors for a *1 t |, e QiO'bhour, and strain ; then gradually add Solution of Ammonia to precip lta tura ted jWash this until nothing alkaline is perceptible. Let what remains be sa Ani 111 , (the rest of the Sulphuric Acid , diluted. Afterwards digest with two < \ unC ya pora te 1Charcoal, and strain. Lastly, the Charcoal being thoroughly washed, e rliquor cautiously, that crystals may be produced.