THE WHITE POPPV.

1299

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Urc ; thra , cutis vera, w ounds or ulcers, it first causes pain, a sense of'' e! 'hen ^diammation ; but these effects subside, and are followed by a^ tV( Tu]^ ° r . a P ai-a lytic condition of the sensitive and motor nerves.

Hie lle Physiologists have proved that opium causes a local paralysis ofHie n ar '> anc l Muller ( Phys. by Baly, vol. i. p. 630) has shewn thatWancp °*' 1C f c t' on is not propagated from the trunk of a nerve to its,l| i ,1 utes' S 'tv 1 ^ runi P e (°P- supra cit.) shewed, that, at the end of thirty)Us C( ,. | ,.’ he eye to which opium had been applied was somewhat lessq 1 e °t the action of alcohol. Scarcely any obvious effect resultsthe b ar ■ application of opium to the ordinary integument, on account ofa te i nil r P res ented by the cuticle. Employed endermically the effects. l 1 o^ ' TOOre Powerful.

l *° s e oh IOR7EM Appearances. —The most important appearances arese rvedin the nervous system; such as turgescence of vessels,

l illTIiAIXAPH/rjO, xnv - —X 1 --

‘"sion Se ^. ve ^in the nervous system; such as turgescence ... .

fare ly „ ° wa ter or of coagulable lymph, and occasionally, thoughWli ( ., ) Xtravasati °i 1 of blood.

'-Triljlg * e ' ? re< l ness the digestive canal is observed, I believe it is re-e -? t le use of some irritants (such as spirits, ammonia, or emetics)il°jj c ^ with, or after the use of, opium.

V!’ f,i;andi - —Under this head I propose to examine several

of

a °t hitherto noticed, and which involve the theory of the operation

This

I. pj 1 ° n the system.a Sse r} ; le ydorous and Active Principles of Opium are absorbed.°u is proved by the following facts:—

«.!;•> T *>

W WelU Ur °F ) i um 1S sometimes recognizable in the secretions and exhalations ;

U hv . . 0WT1 that the opiate odouris frequently detected in the breath ofpersons

- ,a v *■' ' izs drujr; and Barbier (Traite Elem. de Mat. Med . ii. 732, ed.) states,

{b \ a lso noticed in the urine and sweat. . . r? i *

*ecretion*, in some cases, appear to possess narcotic properties• Barb.erSrs-/ lll « case of an infant who was thrown into a state of narcotism of seieial'“^cl a dU ; aUon 'in consequence of having sucked a nurse who had previously swal-

(c.; n r ° se of laudanum lo relieve a cramn ol the stomach.s tr,

4

(e.)jj c . ..,_

'°yed t)y Con . ,c acid was detected, by two of my pupils, in the urine of a rabbit de-vil ir °P , utn.

- ' ’ °arru e ] ;

I,. ' 11 fluence el f !ISSertS *H a t he detected morphia in the blood and urine of a person under11 °Htain»|°i a poi»nous dose of laudanum. As, however, these results have notPy Dublanc or Lassaigne, the statement is not to be absolutely relied on.

H

>uJ he Constitutional Effects of Opi,this n ’ 071 the absorption of its active principles.

. Option rests, arela.) Xh

.14.) T|, e act >ve principles of opium are absorbed. ahsorbinw

5 constitutional effects of it are found to be proportionate to the absorb.n,

»Pium, when thrown into the jugular vein, is similar to, though

v Id.) -.^rUl than, that produced by its application to other parts of the body.

Si,',, Uie narcotic acL, a.... -.act from a particular point of a nerve on tne

um depend in great part , if notThe facts on which

(MaiT l,l:0tic act ' on does not re-

^ ■!, p^

u, & sential and Primary Operation of Opium is on the Nervous

**t'uin n s'...... 7 t ,./ ,, 7.7 ./7, .\ 'I' 1.1.i I,m. i i c Timvorl hv

i Phys. by Baly, i. 631.

'Cj'othe

*«u. . dhe

am and Spinal Cord chiefly ).—This axiom is proved byalready described effects of opium. An examination ol

hi

ncC« important effects of opium arc direct and obvious lesions of the tier-