ACONITE.

1339

re 1S Q n lminet \i ate ly preceding death, is not well onserven. r m me nmiiL>th e rabbits do not answer well for demonstrating these effects; andea ™ess (paralysis ?) of the hind extremities, and spasmodic move-«odL a J e much more marked in them than in dogs. I can distinguishthose e / 0nce between the effects of Aconitum Napellus on rabbits andPf; t i 0 Aconitum ferox on the same animals (see the results of my ex-011 tt ]e latter plant, in the splendid work of my friend Dr.the fir’ ^ antce Rariores Asiatics; also a detail of my experiments in°Peni <Wl ^‘ ^ ourn - °f R~ at - an d Geogr: Science , July 1830, p. 235). On]H,1 the bodies of dogs killed by aconite, immediately after death, no4 hsta' l0llS the heart are visible.—Want of space compels me tooji „ 111 from entering into any details respecting the experiments made(tVii. 1Umals w 'tli aconite by Wepfer {Hist. Cic. Aq. 1733), SproegelW"?’ Wirk. d. Arzneim. u. Gifte. Bd. i. S. 33), Viborg (ibid. S. 34);

\ lG Trans, for 1811, p. i78), and Orfila {Toxicol. Gen.)

If a j ) } n man.—The topical effects are peculiar and most remarkable.''Icr)l,„i7 °. r a srn all portion of the root be chewed, or a few drops of the; tincture of the root be applied to the lips, there are produced in— 1 ~ '-l-w,m tbudina- sensation. These

^fe\v * Unciure 01 me rooi uu UCU lu miu * * y ,... 7 t

efie c ^ lninu tes numbness and a remarkable tingling sensation. These*0«dure for many hours. If the quantity taken into the month be4pp e lal larger, the palate and throat are affected. To me the sensation<Jo ts „ S as 11 the velum and soft palate were elongated, and rested on theSw^ji ,n °1 tlie tongue. To relieve this, frequent attempts are made to

^hen Cn srn(J R and repeated doses of the alcoholic tincture of the root areCities lnternal ly’ llle y cau se a sensation of heat and tingling in the extre-

'1'he ai1 ^ occasionally slight diuresis,

ext ract of aconite of the shops is but little to be relied on. Many

I )r ° ( luce neither numbness nor tingling when rubbed on the lips"nq ^ Storck ( Essay on the Int. Use of the Thorn-Apple, Henbane,

'Wm- ° n ' ' ’ '■'•is ns a dianhoretic and

(In ttlc -

vs/iood, Lonrl. suiies LilcJlt It ttVW wvs. - - A

dUcefp- These symptoms, however, are by no means constantly pro-ton;*’ and > when thev occur, are not always clearly refemble to thej ait e used.

^ > h( i Jy 0lsrjnons doses the effects of aconite are most remarkable. The

Hg 1 1 ~ -fowiltr nf tlirpp, ni

aose $ UU5 eiieuis VJ± UWHllv --

" er(i fu" S - (lelails C) l' H ie effects produced on a family of three(Jlrg. p llls hed me, a few days after the accident, by one of thehoi . lescottb and her account was confirmed by a very ii

three personssufferers

■ ^4}$ yj tew days aner me ucbiututj v.— —

MgjA lef »cott), and her account was confirmed by a very intelligent°ur who witnessed the progress of the symptoms:—

In j\

J'cden 1836, Mr. Prescott, aged 57, residing- in the City Road, planted in his

P' e ces of horse-radish. On February 5th, 1837, he observed some green.V* 11 '( s *tm 1 1 '“i su PP«sed to be those of horse-radish. He dug up three of them. ThetoHlus) CS °* ' v bicb were given me, and have yielded me thriving plants of AconitumV ' that of C f C Utp-sbaped and small. Perhaps a very small walnut would exceed inVr 1 s< »ne - t le " b°le root. These roots were washed, scraped, placed on a platetlil ( a ged V ri l , e S ar ’ a,| d eaten at dinner (at 2 o’clock) with roast beef, by Prescott, hisu anj I |'> an( l child (aged 5). It was remarked at dinner that the root was veryla d not tlie pungency of horse-radish. After the family had dined, about one