1370

ELEMENTS OF MATERIA MEDICA.

ilfl 1

(a.) Action on the urino-genital system. —The pain in the ' oinS ’ t0 iii»the alteration in the quantity and quality of die urine, are the syioP ^indicative of the inflamed condition of the kidneys. The burning r $and tenderness in the hypogastric region, and the constant desirethe urine, with the inability of doing so except drop by drop, are eviof the vesical inflammation. The action on the genital organsmale is proved by priapism, which is sometimes accompanied ^riasis, sometimes not,; and by the occasional inflammation and Ra-tion of the external organs. In the female, the action on the sexntern is shewn by the local heat and irritation, and by the occa*occurrence of abortion. 0 f

(b.) Action on the nervous system. —The affection of this s ) [lieproved by the pain in the bead, disordered intellect, manifestedform of furious or phrenitic delirium, convulsions of the tetanic * lUsubsequently coma. It is deserving of especial notice, that sou* ^several days elapse before the nervous symptoms show themselves- j )C rin a case related by Givdio, they appeared on the third day ; iu a bjinstance, mentioned by Graaf, on the eighth ; and in a case 111 ..poi 1 ’Dr. Ives, they were not observed until the fourteenth day (see Cm 15Treat, on Poisons). j fit”

(c.) Action on the vascular system. —The pulse becomes hard *“ ,.»■queut, the skin hot, and the respiration quickened; diaphoresis issionally observed. , lL iii'

The susceptibility to the influence of canlliarides is by no meall , 5 ,,it! 1form. Werlhoff mentions the case of a lad who used to be attache 1( j-priapism and involuntary emission by merely smelling the powder- ^ inreux says, in one case a pinch of the powder caused death; ndVtanother a spoonful occasioned only slight heat in the throat anmime. Dr. Hosack has mentioned an instance in which a null *..,[ iWnearly six ounces of the tincture with the view of self-destruction)^^,,; ndangerous symptoms followed. In contrast with this, I may h lS t iijf'.case that came within my own knowledge, where one ounce of 1 1 ^ otture produced serious symptoms. Orfila has seen twenty-four g 1the powder prove fatal. . ^ a* 1 ’

1. Action in small or medicinal doses. —In very small quantities u jyl

no obvious effects. If we increase the dose, a sensation of warnit ^^jiiin the throat, stomach, and respiratory passages, w ith increased ge ii-from the alimentary tube. By continued use, a tickling or tin’

sation is experienced in the urethra, with frequent desire to p fnurine, which may or may not be altered in quality and quant 1 . , js

some cases diuresis is observed, in others not: in the latter thegenerally higher coloured than usual. Occasionally the sexual

are excited. g ill*

2. Action in larger doses: Subacute poisoning. —The sympt°heat in the throat, stomach, intestines, and respiratory passage*in the loins, burning sensation in the bladder, with frequen

to evacuate the urine, which is sometimes bloody, and P aS j’ e jii^’difficulty. Painful priapism, with or without satyriasis. 1 u s gys^"*frequent, skin hot, and the respiration quickened: the nervousis frequently excited.

3. Action in still larger doses: Acute poisoning. —The syiup 1