742
ELEMENTS OF MATERIA MEDICA.
analyzed the scales and lupulinic grains,vol. xi. p. 205) also examined the latter.
traces.
99*30
Ives’s Analysis.
Lupulinic Grains,
Payen, Clievallier, and Pelletan’sAnalysis.
Volatile oil.2*001 Tannin
Bitter principle (Lupulite) 10*30
Resin.50 to 55*001 Extractive
Lignin.32*00
Fatty, astringent, and^gummy matters, osma-zome, malic and car-bonic acids, severalsalts (malate of lime ,)acetate of ammonia,chloride of potassium,sulphateof potash) &c.
4*16
8*33
Bitter principle 9*16
WaxResin .Lignin
10*00
30*00
38*33
Payen, Chevallier, and Pelletan 8Analysis.
Astringent matter.
Inert colouring matter.Chlorophyile.
Gum.
Lignin. ^
Salts (of potash, lime, andcontaining acetic, hydrochloric*phuric, nitric, &c. acids). - otlThe scales usually contain a ijjj jt
100*00
of lupulinic matter, from 'is almost impossible to free
tbe^*
1. Volatile Oil of Hops. — Resides in the lupulinic grains. Obtained by submit^
these, or hops which contain them, to distillation with water. Its colour is ? e | O jjolits odour that of hops, its taste acrid. It is soluble in water, but still more so in jC t
and ether. Its sp. gr. is 0’910. By keeping, it becomes resinified. It is said j],
on the system as a narcotic. The water which comes over, in distillation, with tncontains acetate of ammonia, and blackens silver; from which circumstance the rsence of sulphur is inferred. . d> e
2. Bitter Principle of Hops: Lupulite j Lupuline. — Is procured by treating. a |.
aqueous extract of the lupulinic grains, united with a little lime, with alcohol. 1 j ftecoholic tincture is to be evaporated to dryness, the residue treated with water,solution evaporated. The residue, when washed with ether, is lupulite. It * ig'i' 1tallizable, yellowish-white, very bitter, soluble in 20 parts of water, very solualcohol, and slightly so in ether. The aqueous solution froths by agitatiou; . s no
no precipitate with either tincture of nutgalls or acetate of lead. Lupulite j to
nitrogen. It is devoid of the narcotic property of the oil. In small doses it I s t JjC
have caused loss of appetite and diminished digestive power; but a repetitionexperiment is very desirable. ur e 10
3. Resin. —Is of a golden-yellow colour, and becomes orange-yellow by eX P® e j jn l£lthe air. It is soluble in both alcohol and ether. It appears to be the oil chan gresin, partly by oxidizement.
1 itm® 8 ’
Chemical Characteristics. —A decoction of hops reddens n ^owing to the presence of free acid. Sesquichloride of iron strikolive-green colour ( tannate of iron). A solution of gelatin render® 9 ,.filtered decoction turbid ( tannate of gelatin). Chloride of bariumsions with it a white precipitate ( sulphate of baryta). Oxalate 0monia also causes a white precipitate ( oxalate of lime.) ^ th c
Physiological Effects. —The odorous emanations (vapour .volatile oil) of hops possess narcotic properties. Hence a pillow °cones promotes sleep, as I have several times witnessed. Moreo'are told that stupor has occasionally been induced in persons wuremained for a considerable time in hop warehouses.
The lupulinic grains are aromatic and tonic. They appear , g(r
possess soothing, tranquillizing, and, in a slight degree, sedative ^porific properties. But the existence of any narcotic quality ^^ reJl S estrongly denied by Dr. Bigsby ( Land. Med. Rep. vol. iv. p. 287), ^ a f C yl3"{Formulaire ), and others. “ I have tried, at different times,’ sa ' ^ jtsgendie, “ both the lupuline [lupulinic grains] in substance, 1111