1008

ELEMENTS OF MATERIA MEDICA.

la

chres,i “nd*rnil'

thus Dr. Darwin strewed it in the patient’s bed.

Methode Iatralept. 232 and 270) successfully used the tincture gholic extract by the iatraleptic method (see p. 48). More recenphate of quinia has been employed in the same way. The la . fai.tioned preparation has also been applied by the endermic method l ^ j sGen. de Med. 1826 ; Revue Med. 1827): but this mode of usWS^sometimes attended with intense pain and an eschar (Trousse e j„Pidoux, Traite de Therap. ii. 219). To infants at the breast, ^ ose aC tiv®advises its indirect exhibition by the nurse , in whose milk lJS ' gU l-principle is administered to the child [Ibid. 231). More recenphate of quinia mixed with tobacco (in the proportion of 15 g rS ; j^erformer to an ounce of the latter) has been employed as a snuff 111mittent headache. . j e of

Cinchona and its preparations prove most successful in the si F arSuncomplicated form of intermittents ; that is, where the disease Ftj aJJ) .to be purely nervous. But when agues are accompanied u'ltn , e smatory excitement or with Visceral diseases, cinchona generally Feither useless or injurious. In remittents it proves much less sue ul -than in regularly-formed intermittents. In all these cases we en t j , eto promote the efficiency of the cinchona by reducing the disease 0 fform of a pure or simple intermittent. The means to effect this i ^tlicourse depend on a variety of circumstances; but blood-lettiUcO^ t ],egeneral and local, purgatives, and diaphoretics, are those which r y

Under some circumstances I,ie wlVe s

as a very slight sialogogue;

pr« ve

most part will lie found available,given in alterative doses, or evenbeneficial.

Intermittent fevers are not the only periodical diseases in ^ get'chona has been found beneficial. It is a remedy which has pi -0 ' aS1 n,viceable in several other cases in which a paroxysm (of pain?

ivhic» cin '

,b-

inflammation, hemorrhage, or fever) returns at stated periods. ^intermittent neuralgia, rheumatism, headache, amaurosis, c atari ? 0 fthalmia, stricture, &c. have been greatly benefitted by its use. ,- 0( Jicalthese affections have been regarded as masked agues. When p el ^ al --diseases recur at uncertain periods, as in the case of epilepsy?ticular advantage can be expected from the use of cinchona. wb e!1

2. In Continued Fever. —In the latter stage of continued fe' r er> j. e clthe vital powers are beginning to sink, and where there is n0 .ff eS ^\'eand decided symptom of inflammatory disease of the brain ororgans, cinchona or sulphate of quinia sometimes proves highly n ( j rV)cial. If the tongue be dry, as well as furred, and the skin hot an t .

indisti^the i»° l ;circa®?

no advantage, but the reverse, can be anticipated from its einpl°).‘“

It is most applicable to the low forms of fever occurring mconstitutions. When exacerbations or remissions, howeveroccur at regular periods, the administration of cinchona islikely to be followed by good effects. Under the preceding

of bai-

lo

diniif

stances there can scarcely be two opinions as to the admissibilityBut on the general propriety of administering this remedy in c l ° i. 0afever, considerable difference of opinion has prevailed (Clutterbu, ’ j el jthe Seat and Nature of Fever, 399, 2nd edit. 1825). Dr. ^ e e pjaS{Comment.) cautiously observes, “ I am not so sure of its being u c jj,I am of its being innocent.” In order to avoid offending the^s

av

it is frequently advisable to begin with the infusion

for w

hich after'