228

* Probably SitWilliam Pet'ty-

Philosophical'Transactions,No. 7. p.128.1665.

»

THE LIFE OF

It should seem, by the Date, and a Paragraph in a Letter to a Personof Distinction in Ireland *, he made the first Experiment of Infusion , aboutthe Year 1656. After the Recital of several new Experiments in Philoso-phy, and Anatomy, he thus proceeds, — " The most considerable Experi-" ment I have made of late, is this; I injected Wine and Ale into the Mass" of Blood in a living Dog, by a Vein, in good Quantities, till I made him" extremely drunk, but soon after he pissed it out: With two Ounces of" Infusion of Crocus Mctallorum thus injected, the Dog immediately fell" to vomiting, and so vomited till he died. It will be too long to tell you the" Effects of Opium , Scammony, and other Things which 1 have try’d this" Way. I am in further Pursuit of the Experiment, which I take to be of j" great Concernment, and what will give great Light to the Theory and'

" Practice of Physick. I

An Account of the Rife and Attempts of a Way to convey hi-quors immediately into the Mass of Blood.

W Hereas there have lately appear’d in publick some Books, printed be-yond the Seas, treating of the Way of injelding Liquors into Veins',in which Books the Original of that Invention , seems to be aferib’d to others,besides him, to whom it really belongs; it will surely not be thought amissif something be said, whereby the true Inventor’s Right may beyond Ex-ception be asserted and preserv’d ; to which End, there will need no more,than barely to represent the Lime when, and the Place where, and amongwhom it was first started, and put to trial. To join all these Circumstancestogether, ’tis notorious, that at least six Years (a good while before it washeard offj that any one did pretend to have ib much as thought of it) thelearned and ingenious Doctor Christopher Wren did propose in the Universityof Oxford, (where he now is the worthy Savilian Professor of AJironomj , andwhere very many curious Persons are ready to attest this Relation) to thatnoble Benefactor to experimental Philosophy, Mr. Robert Boyle, Dr. Wilkins ,and other deserving Persons, that he thought, he could easily contrive aWay, to convey any liquid Thing immediately into the Mass of Blood, videlby making Ligatures on the Veins, and then opening them on the Side ofthe Ligature towards the Heart, and by putting into them slender Syringes,or Quills, fasten’d to Bladders (in the Manner of Clyster Pipes) containingthe Matter to be injected; performing that Operation upon pretty big andlean Dogs, that the Vessels might be large enough, and easily accessible.

This Proposition being made, Mr. Boyle soon gave Order for an Appara-tus, to put it to Experiment ; wherein at several Times, upon several Dogs,Opium, and the Infusion of Crocus Metallorum were injected into that Partof the hind Legs of those Animals, whence the larger Vessels, that carrythe Blood, are most easy to be taken hold of; whereof the Success was,that the Opium being soon circulated into the Brain, did within a ssiodTime stupify, tho’ not kill the Dog; but a large Dose of the Crocus Metal"lorum,' made another Dog vomit up Life and all: all which is more amplyand circumstantially deliver’d by Mr. Boyle, in his excellent Book of th eUsefulness of experimental Philosophy, Part 2. Postscript to Essay 2. Where’tis also mention’d, that the Fame of this Invention , and of the succeedingTrials being spread, and particularly coming to the Knowledge of a foreig 11 jAmbassador, that was curious, and then resided in London, it was by hid 1 Jtried with some Crocus Metallorum, upon a Malefactor, that was an inst" .riour Servant of his; with this Success, that the Fellow, as soon as ever the :

In

Sv

th,

At

Ti

be:

cia

Ex

ser

tea

M<

anc

flic

Ve.

Blc

otb

the

Ha

Hsi

Em

can

dot

rati

day- sidefror

Cot

Oxj

que

birr

Mi

1

peri

Hat

ing

Wr

the

Mr.

he £dtece xtrpto>Witi

w a

Eirf

Jr e g

holt